In certain individuals, particularly at higher doses, ARCOXIA may elevate blood pressure, which may raise the likelihood of heart attacks and strokes. To ensure the safety of ongoing treatment, your physician may periodically monitor your blood pressure.ARCOXIA is effective in alleviating pain and inflammation in the muscles and joints of individuals aged 16 years or older who suffer from osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout.